A photo ID is now required to buy e-cigarettes, and their sale in all-ages vending machines is not permitted in the US. E-cigarette and tobacco companies have recruited lobbyists in an effort to prevent the US FDA from evaluating e-cigarette products or banning existing products already on the market. As of 2015, research had not yet provided a consensus on the risks of e-cigarette use. There is little data about their safety, and a considerable variety of liquids are used as carriers, and thus are present in the aerosol delivered to the user.

Given that most smokers who switch to e-cigarettes begin with either tobacco or menthol flavors,10 other flavor categories that attract youths are likely unnecessary. Tellingly, only 1 individual in the study by McKelvey and colleagues2 reported that their first pod was tobacco flavored. JUUL recently began selling lower nicotine concentrations for 2 flavors , but not for their other fruit and dessert flavors that may directly appeal to adolescents. If left unaddressed, the combination of appealing flavors and high nicotine concentrations in pod mods could undermine tobacco control efforts. Results reported here revealed that the new generation of pod designs and formulations of the popular pod liquids do not necessarily provide a decrease in toxic metal concentrations in aerosols compared to previous designs. All the aerosol metals detected may represent health risks for ENDS users; however, there is limited evidence for specific dose/response disease relations.

Research suggests vaping is bad for your heart and lungs

The company changed its name to Ruyan (如烟, literally “like smoke”) later the same month, and started exporting its products. Many US and Chinese e-cigarette makers copied his designs illegally, so Hon has not received much financial reward for his invention (although some US manufacturers have compensated him through out-of-court settlements). Ruyan later changed its company name to Dragonite International Limited. As of 2014, most e-cigarettes used a battery-powered heating element rather than the earlier ultrasonic technology design. Harm reduction refers to any reduction in harm from a prior level.


However, we agree that the neuroinflammation is of great interest and is highly likely to impact behavior and mood. Further studies are needed to best assess potential psychological and behavioral changes. บุหรี่ไฟฟ้า pod believe this work is important to share such that dedicated behavioral science labs can undertake these important studies. We have added further discussion regarding the potential consequences of inflammation in each of the organs (pages 13-19), with an emphasis on the effects of neuroinflammation on behavior and psychology. Thank you for the detailed review of this original research manuscript. We appreciate the reviewer identifying it as “of high interest and timely.” Of note, part of working in a new field such as e-cigarettes involves assessing for and detecting signals of potential clinical relevance.

It uses a coil to heat a liquid that produces a vapor that moves through mixed tobacco. Heated tobacco products were first introduced in 1988, but were not a commercial success. In November 2020, the New Zealand government passed a vaping regulation that requires vape stores to register as specialist vape retailers before they can sell e-cigarettes, the wider range of flavoured e-liquids, and other related vaping products. Vaping products are required to be notified by the government before they can be sold to ensure that the products are following safety requirements and ingredients in liquids do not contain prohibited substances. As of 2020, the efficacy and safety of vaping for quitting smoking during pregnancy was unknown.